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Pulmonary Drug Delivery

Author: Ali Nokhodchi
Publisher: John Wiley & Sons
ISBN: 1118799526
Category : Science
Languages : en
Pages : 384

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Book Description

Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.

Controlled Pulmonary Drug Delivery

Author: Hugh D.C. Smyth
Publisher: Springer Science & Business Media
ISBN: 1441997458
Category : Medical
Languages : en
Pages : 558

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Book Description
The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.

Pulmonary Drug Delivery

Author: Ali Nokhodchi
Publisher: John Wiley & Sons
ISBN: 1118799526
Category : Science
Languages : en
Pages : 384

View »

Book Description
Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.

Controlled Pulmonary Drug Delivery

Author: Hugh D.C. Smyth
Publisher: Springer
ISBN: 9781441997463
Category : Medical
Languages : en
Pages : 558

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Update on Polymers for Pulmonary Drug Delivery

Author: Hugh D. C Smyth
Publisher: Smithers Rapra
ISBN: 1847356559
Category : Medical
Languages : en
Pages : 285

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Book Description
Pulmonary drug delivery has been a rapidly expanding field, moving from the traditional propellant based metered dose inhaler delivery of small asthma drugs, to a broader landscape of new devices and novel drugs for local and systemic delivery. The field has greatly expanded yet the tools for pulmonary drug delivery systems have not kept pace with the potential applications. One of the key developments has been the use of polymers to achieve better control of pulmonary drug delivery. This has the potential to expand the toolbox available for researchers in the field to deliver their new chemical entities successfully to the lung. This book reviews the use of polymers in pulmonary drug delivery, encompassing polymers from their use in devices and packaging, in addition to their use as excipients in formulations delivered to the airways. The book is arranged by application and extensively reviews the technical and patent literature. This is the first volume totally dedicated to polymers in pulmonary drug delivery and should be the resource of choice for those in the field, especially managers in the pharma/biotech industry. Naturally, the text will be of great interest to academics and graduate students. Finally, regulatory affiliated scientists will also find this resource invaluable.

Advances in Pulmonary Drug Delivery

Author: Philip Chi Lip Kwok
Publisher: CRC Press
ISBN: 131531195X
Category : Medical
Languages : en
Pages : 246

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Book Description
The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generally more sophisticated than those for oral and parenteral administration. Pulmonary drug development is therefore a highly specialized area because of its many unique issues and challenges. Rapid progress is being made and offers novel solutions to existing treatment problems. Advances in Pulmonary Drug Delivery highlights the latest developments in this field.

Handbook of Lung Targeted Drug Delivery Systems

Author: Yashwant Pathak
Publisher: CRC Press
ISBN: 1000450767
Category : Medical
Languages : en
Pages : 692

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Book Description
Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals. Key Features: Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research. Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications Examines specific formulations targeted to pulmonary systems

Inhalation Drug Delivery

Author: Paolo Colombo
Publisher: John Wiley & Sons
ISBN: 1118397169
Category : Science
Languages : en
Pages : 216

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Book Description
There has been a rapid evolution in the field of inhalation drug therapy, including new drugs, increased regulation and quality control, and strong pressure from generics. Inhalation Drug Therapy brings together the most current inhalation drug research, as well as practical developments and processes, into one essential guide. Focusing on inhalation products and specific equipment and techniques used in manufacturing and quality control, the book balances research with the industrial aspects of creating the drugs, and features a highly regarded author team with both academic and industry experience.

Pulmonary Drug Delivery

Author: Karoline Bechtold
Publisher:
ISBN: 9783871933226
Category :
Languages : en
Pages : 412

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Book Description

Pulmonary Drug Delivery

Author:
Publisher:
ISBN:
Category : Lungs
Languages : en
Pages : 27

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Book Description

Nanoparticle For Pulmonary Drug Delivery System

Author: Priya Patel
Publisher: LAP Lambert Academic Publishing
ISBN: 9783659417337
Category :
Languages : en
Pages : 68

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Book Description
A new value paradigm is taking shape in the drug delivery market. Nanotechnology delivery techniques will shape the future of drug delivery. "Nanotechnology-enabled drug delivery systems (DDS) over the next ve years are forecast to dramatically reshape the way existing drugs are delivered." The growing range of nanotechnology enabled drug delivery methods is poised to change the way new compounds are formulated, and to extend the life cycle of existing compounds. Nanoparticles hold promise as therapeutic agents for a number of diseases. In this book give a brief introduction regarding pulmonary drug delivery system. Determining the physicochemical characteristics of inhaled nanoparticles on their ability to cross the lungs alveolar epithelial surface is an important step in understanding the biological effects associated with exposure to these particles.