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Homeostatic Control of Brain Function

Author: Detlev Boison
Publisher: Oxford University Press
ISBN: 0199322295
Category : Medical
Languages : en
Pages : 642

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Book Description

Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include - A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. - Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. - Incorporation of homeostatic therapies into existing basic and clinical research paradigms. - Extensive scientific basic and clinical research ranging from molecules to disorders. - Emerging practical information for improving homeostasis. - Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.

Homeostatic Control of Brain Function

Author: Detlev Boison
Publisher: Oxford University Press
ISBN: 0199322295
Category : Medical
Languages : en
Pages : 642

View »

Book Description
Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include - A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. - Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. - Incorporation of homeostatic therapies into existing basic and clinical research paradigms. - Extensive scientific basic and clinical research ranging from molecules to disorders. - Emerging practical information for improving homeostasis. - Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.

Metabolic Control of Brain Homeostasis

Author: Detlev Boison
Publisher: Frontiers Media SA
ISBN: 2889452867
Category :
Languages : en
Pages :

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Book Description
Brain function is under metabolic control, which in turn determines the equilibrium of homeostatic systems that affect neuronal and glial networks on the molecular, cellular, and systems levels. The collection of articles ranges from molecules and mechanisms involved in regulating homeostasis and neuronal excitability to therapeutic mechanisms tailored to restore homeostatic function. It also features neurological diseases and novel treatment approaches that are based on metabolic and homeostatic interventions. Together, the collection of articles outlines novel strategies to restore brain function in neurology and highlights limitations of conventional pharmacological approaches. We suggest that restoration of molecular and biochemical networks could lead to a new era of therapeutic opportunities.

Neural Control of Energy Homeostasis and Energy Homeostasis Regulation of Brain Function

Author: Lionel Carneiro
Publisher: Frontiers Media SA
ISBN: 2889760030
Category : Science
Languages : en
Pages :

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Book Description

Cerebellum and Cerebrum in Homeostatic Control and Cognition

Author: Eric Parkins
Publisher: Routledge
ISBN: 1000481123
Category : Psychology
Languages : en
Pages : 256

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Book Description
Cerebellum and Cerebrum in Homeostatic Control and Cognition presents a ground-breaking hybrid-brain psychology, proposing that the cerebellum and cerebrum operate in a complementary manner as equal cognitive partners in learning based control. The book synthesises contemporary neuroscience and psychology in terms of their common underlying control principle, homeostasis. Drawing on research and theory from neuroscience, psychology, AI and robotics, it provides a hybrid control systems interpretation of consciousness and self; unconscious mind; REM dream sleep; emotion; self-monitoring and self-control; memory, infantile amnesia; and, cognitive development. This is used to investigate different elements of cerebellum-cerebrum offline interaction; including attention and working memory, and explores cerebellar and cerebral contributions to various aspects of a number of disorders; including ADHD, ASD and schizophrenia. Presenting original ideas around neuropsychological architecture, the book will be of great interest to academics, researchers, and post-graduate students in the fields of neuropsychology, cognitive psychology, neuroscience and clinical psychology.

Volume 5 - Animal Structure and Function

Author: Cecie Starr
Publisher: Cengage Learning
ISBN: 1305724771
Category : Science
Languages : en
Pages : 304

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Book Description
Written by a team of best-selling authors, BIOLOGY: THE UNITY AND DIVERSITY OF LIFE, 14th Edition reveals the biological world in wondrous detail. Packed with eye-catching photos and images, this text shows and tells the fascinating story of life on Earth, and engages readers with hands-on activities that encourage critical thinking. Chapter opening Learning Roadmaps help you focus on the topics that matter most and section-ending Take Home Messages reinforce key concepts. Helpful in-text features include a running glossary, case studies, issue-related essays, linked concepts, self-test questions, data analysis problems, and more. Known for a clear, accessible style, BIOLOGY: THE UNITY AND DIVERSITY OF LIFE, 14th Edition puts the living world of biology under a microscope for readers from all walks of life to analyze, understand, and enjoy! Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

Neuronal mechanisms of epileptogenesis

Author: Roberto Di Maio
Publisher: Frontiers E-books
ISBN: 2889193829
Category :
Languages : en
Pages :

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Book Description

Biology: The Unity and Diversity of Life

Author: Cecie Starr
Publisher: Cengage Learning
ISBN: 1133707610
Category : Science
Languages : en
Pages : 1024

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Book Description
Renowned for its writing style and trendsetting art, BIOLOGY: THE UNITY AND DIVERSITY OF LIFE engages students with relevant applications and encourages critical thinking. The new edition offers a new Learning Roadmap in each chapter to help students gain a full understanding. Students are able to focus on key concepts, make connections to other concepts, and see where the material is leading. Helpful learning tools like the section-ending Take-Home Messages and the on-page running glossary ensure they grasp key points. Carefully balancing accessibility and the level of detail, the authors enable students to go beyond rote memorization and prepare them to make important decisions in life that require an understanding of biology and the process of science. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

Homeostatic and Retrograde Signaling Mechanisms Modulating Presynaptic Function and Plasticity

Author: Michael A. Sutton
Publisher: Frontiers Media SA
ISBN: 2889197042
Category :
Languages : en
Pages :

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Book Description
Activity within neural circuits shapes the synaptic properties of component neurons in a manner that maintains stable excitatory drive, a process referred to as homeostatic plasticity. These potent and adaptive mechanisms have been demonstrated to modulate activity at the level of an individual neuron, synapse, circuit, or entire network, and dysregulation at some or all of these levels may contribute to neuropsychiatric disorders, intellectual disability, and epilepsy. Greater mechanistic understanding of homeostatic plasticity will provide key insights into the etiology of these disorders, which may result from network instability and synaptic dysfunction. Over the past 15 years, the molecular mechanisms of this form of plasticity have been intensely studied in various model organisms, including invertebrates and vertebrates. Though once thought to have a predominantly postsynaptic basis, emerging evidence suggests that homeostatic mechanisms act on both sides of the synapse through mechanisms such as retrograde signaling, to orchestrate compensatory adaptations that maintain stable network function. These trans-synaptic signaling systems ultimately alter neurotransmitter release probability by a variety of mechanisms including changes in vesicle pool size and calcium influx. These adaptations are not expected to occur homogenously at all terminals of a pre-synaptic neuron, as they might synapse with neurons in non-overlapping circuits. However, the factors that govern the homeostatic control of synapse-specific plasticity are only beginning to be understood. In addition to our limited molecular understanding of pre-synaptic homeostatic plasticity, very little is known about its prevalence in vivo or its physiological and disease relevance. In this research topic, we aim to fill the aforementioned void by covering a broad range of topics that include: - Identification of signaling pathways and mechanisms that operate globally or locally to induce specific pre-synaptic adaptations - The nature of pre-synaptic ion channels relevant to this form of plasticity and their synapse-specific modulation and trafficking - Development and utilization of new tools or methods to study homeostatic plasticity in axons and pre-synaptic terminals - Novel mechanisms of homeostatic adaptations in pre-synaptic neurons - Postsynaptic sensors of activity and retrograde synaptic signaling systems - A comprehensive analysis of the kinds of pre-synaptic adaptations in diverse neural circuits and cell types - Identification of physiological or developmental conditions that promote pre-synaptic homeostatic adaptations - How activity-dependent (Hebbian) and homeostatic synaptic changes are integrated to both permit sufficient flexibility and maintain stable activity - Relevance of pre-synaptic homeostatic plasticity to the etiology of neuropsychiatric disorders - Computational modeling of pre-synaptic homeostatic plasticity and network stability.

A Physiological Handbook for Teachers of Yogasana

Author: Mel Robin
Publisher: Wheatmark, Inc.
ISBN: 1587360330
Category : Health & Fitness
Languages : en
Pages : 652

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Book Description
This illustrated handbook attempts to reconcile the quantitative, objective observations of Western Medicine with the qualitative, subjective observations of Eastern Yoga.

Stress and Animal Welfare

Author: D.M. Broom
Publisher: Springer
ISBN: 9402409807
Category : Science
Languages : en
Pages : 211

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Book Description
Stress and Animal Welfare provides students of animal biology with a fresh, integrated coverage of the concepts and scientific measurement of the welfare of animals. This book is the first to explain the basic biological principles of how animals actually cope with stress, and the major part of the work is devoted to explaining scientifically usable concepts in stress and welfare. A wide range of stress indicators are highlighted in detail with examples being drawn from man and other species. This information forms the basis for a synthesis of now ideas presented here for the first time. Among the issues covered are: •how physical systems are regulated by the body and brain; •limits to adaptation •assessing welfare for both short-term and long-term responses; •ethical problems and suggested solutionsProper assessment of animal welfare is essential so that informed decisions can be taken about what is morality acceptable in terms of practice and in the development of more effective legislation. This text encapsulates a very wide body of literature on scientific aspects of animal welfare, and will prove a valuable asset for students and teachers of animal biology.